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Hirofumi Kawanaka Selected Research

Liver Cirrhosis (Hepatic Cirrhosis)

11/2016Pancreatic fistula after laparoscopic splenectomy in patients with hypersplenism due to liver cirrhosis: effect of fibrin glue and polyglycolic acid felt on prophylaxis of postoperative complications.
8/2015Laparoscopic Splenectomy with Technical Standardization and Selection Criteria for Standard or Hand-Assisted Approach in 390 Patients with Liver Cirrhosis and Portal Hypertension.
6/2015Liver transplantation followed by pulmonary resection complicated with end-stage liver cirrhosis: a case report.
11/2014Optimizing risk stratification in portal vein thrombosis after splenectomy and its primary prophylaxis with antithrombin III concentrates and danaparoid sodium in liver cirrhosis with portal hypertension.
10/2013Effect of CD133-positive stem cells in repeated recurrence of hepatocellular carcinoma after liver transplantation: a case report.
6/2012Predictive factors for platelet count after laparoscopic splenectomy in cirrhotic patients.
1/2010Impact of antithrombin III concentrates on portal vein thrombosis after splenectomy in patients with liver cirrhosis and hypersplenism.
1/2009Technical standardization of laparoscopic splenectomy harmonized with hand-assisted laparoscopic surgery for patients with liver cirrhosis and hypersplenism.
3/2008Defective endothelial nitric oxide synthase signaling is mediated by rho-kinase activation in rats with secondary biliary cirrhosis.
5/2007Splenic hemodynamics and decreased endothelial nitric oxide synthase in the spleen of rats with liver cirrhosis.

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Hirofumi Kawanaka Research Topics

Disease

17Neoplasms (Cancer)
02/2021 - 02/2002
14Hepatocellular Carcinoma (Hepatoma)
01/2018 - 09/2009
13Stomach Neoplasms (Stomach Cancer)
01/2022 - 05/2004
12Portal Hypertension
08/2015 - 01/2002
10Liver Cirrhosis (Hepatic Cirrhosis)
11/2016 - 05/2007
9Hypersplenism (Anemia, Splenic)
11/2016 - 01/2009
8Hemorrhage
09/2020 - 01/2008
6Thrombosis (Thrombus)
02/2018 - 01/2010
5Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 01/2016
5Liver Diseases (Liver Disease)
02/2018 - 02/2009
4Esophageal and Gastric Varices (Esophageal Varices)
07/2020 - 12/2013
4Splenomegaly
01/2018 - 09/2009
4Ascites
01/2017 - 07/2008
4Thrombocytopenia (Thrombopenia)
07/2015 - 01/2010
4Esophageal Neoplasms (Esophageal Cancer)
01/2015 - 10/2013
4Fibrosis (Cirrhosis)
12/2014 - 02/2012
4Ulcer
12/2013 - 02/2002
3Varicose Veins (Varicose Vein)
09/2020 - 09/2009
3Carcinoma (Carcinomatosis)
12/2013 - 07/2011
2Disease Progression
01/2022 - 07/2020
2Hypoxia (Hypoxemia)
01/2021 - 02/2002
2Pancreatic Fistula (Pancreatic Fistulas)
11/2016 - 12/2013
2Sepsis (Septicemia)
12/2015 - 08/2015
2Sarcopenia
12/2015 - 10/2014
2Hernia (Hernias)
11/2015 - 12/2013
2Hepatitis C
08/2015 - 06/2012
2Cholangiocarcinoma
04/2015 - 12/2013
2Liver Neoplasms (Liver Cancer)
10/2014 - 10/2013
2Pathologic Constriction (Stenosis)
06/2014 - 11/2013
2Lymphatic Metastasis
12/2013 - 05/2004
2Hepatitis B
10/2013 - 06/2012
1Reperfusion Injury
01/2021
1Nausea
01/2021
1Non-alcoholic Fatty Liver Disease
01/2021
1Vomiting
01/2021
1Neoplasm Metastasis (Metastasis)
09/2020
1Hepatic Veno-Occlusive Disease (Disease, Hepatic Veno-Occlusive)
09/2020
1Obturator Hernia
01/2018
1Waldenstrom Macroglobulinemia (Macroglobulinemia)
07/2015

Drug/Important Bio-Agent (IBA)

5Oxaliplatin (Eloxatin)FDA LinkGeneric
02/2021 - 01/2016
4InterferonsIBA
02/2012 - 09/2009
3Bevacizumab (Avastin)FDA Link
01/2021 - 01/2016
3Irinotecan (Camptosar)FDA LinkGeneric
01/2020 - 01/2016
3Pharmaceutical PreparationsIBA
02/2018 - 01/2013
3Antithrombin IIIIBA
02/2018 - 01/2010
3BilirubinIBA
08/2015 - 07/2008
3Messenger RNA (mRNA)IBA
10/2013 - 02/2002
3Proteins (Proteins, Gene)FDA Link
03/2002 - 02/2002
2Cisplatin (Platino)FDA LinkGeneric
02/2021 - 01/2020
2AnticoagulantsIBA
10/2014 - 04/2012
2SteroidsIBA
03/2014 - 12/2013
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2011 - 02/2002
2Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
03/2008 - 05/2007
2Acetic Acid (Vinegar)FDA LinkGeneric
03/2002 - 02/2002
1PlatinumIBA
01/2022
1RamucirumabIBA
01/2022
1Palonosetron (Aloxi)FDA Link
01/2021
1Oleic Acid (Oleate)IBA
01/2021
1Aprepitant (Emend)FDA Link
01/2021
1trifluridine tipiracil drug combinationIBA
01/2021
1Granisetron (Kytril)FDA LinkGeneric
01/2021
1Dexamethasone (Maxidex)FDA LinkGeneric
01/2021
1AntiemeticsIBA
01/2021
1histidine-rich proteinsIBA
01/2021
1ethanolamine oleate (Ethamolin)FDA Link
09/2020
1SolutionsIBA
09/2020
1Iopamidol (Isovue)FDA LinkGeneric
09/2020
1Trastuzumab (Herceptin)FDA Link
01/2020
1Cetuximab (Erbitux)FDA Link
01/2020
1hydroxide ionIBA
01/2018
1CholesterolIBA
01/2017
1Polyglycolic Acid (Polyglycolide)IBA
11/2016
1Prostaglandins AIBA
11/2016
1Fibrin Tissue Adhesive (Fibrin Sealant)IBA
11/2016
1Leucine (L-Leucine)FDA Link
12/2015
1Isoleucine (L-Isoleucine)FDA Link
12/2015
1Glutamine (L-Glutamine)FDA Link
12/2015
1Amino AcidsFDA Link
12/2015
1Surface Antigens (Surface Antigen)IBA
06/2015
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
05/2015
1Mitogen-Activated Protein KinasesIBA
05/2015

Therapy/Procedure

21Splenectomy
07/2020 - 01/2009
17Liver Transplantation
12/2015 - 01/2008
13Therapeutics
01/2022 - 01/2010
10Drug Therapy (Chemotherapy)
01/2022 - 02/2010
9Hepatectomy
01/2018 - 10/2013
6Gastrectomy
11/2013 - 05/2004
4Ligation
09/2020 - 05/2007
4Esophagectomy
01/2015 - 10/2013
4Adjuvant Chemotherapy
12/2013 - 07/2012
3Length of Stay
11/2015 - 12/2014
3Lymph Node Excision (Lymph Node Dissection)
12/2013 - 05/2004
2Combination Drug Therapy (Combination Chemotherapy)
02/2021 - 01/2016
2Blood Transfusion (Blood Transfusions)
01/2017 - 02/2014
2Surgical Portasystemic Shunt (Portosystemic Shunt)
04/2014 - 06/2007
2Sclerotherapy
12/2013 - 09/2009
2Laparotomy
09/2013 - 05/2009
1Transplantation
01/2021
1Surgical Instruments (Clip)
09/2020
1Urinary Diversion (Ileal Conduit)
09/2020